“However, in a previous study, an exploratory analysis suggested that, in patients taking creatine, caffeine intake was associated with a faster rate of progression.”
“ResultsCaffeine intake was not associated with the rate of progression of PD in the main analysis, but higher caffeine intake was associated with significantly faster progression among subjects taking creatine.”
“These data indicate a potentially deleterious interaction between caffeine and creatine with respect to the rate of progression of PD.”