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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Our main findings were: (1) both caffeine and paraxanthine decreased placental 11β-HSD2 activity, protein and mRNA in a …-mediated knockdown of this receptor prevented caffeine- and paraxanthine-induced inhibition of placental 11β-HSD2; and (3) forskolin (an … both caffeine and paraxanthine, which provides evidence … reduced placental 11β-HSD2.”
Caffeine Reduces 11β-Hydroxysteroid Dehydrogenase Type 2 Expression in Human Trophoblast Cells through the Adenosine A2B Receptor“The Ex vivo study on skin explants showed that caffeine and forskolin both stimulated glycerol release and demonstrates for the first time that retinol and carnitine in combination synergistically stimulated keratinocyte proliferation, which leads to an increase epidermal thickness.”
“The forskolin‐induced potentiation was exacerbated in the presence of caffeine or DPCPX, accentuating the differences between the two areas.”
Characterisation of the mechanisms underlying the special sensitivity of the CA2 hippocampal area to adenosine receptor antagonists“CA release evoked by excess K+, or by caffeine in the presence or absence of external Ca2+ was also potentiated by forskolin.”
“In indomethacin-treated bones, however, caffeine potentiated the stimulatory effect on 45Ca release induced by choleratoxin and forskolin.”
“The inhibitory effect of caffeine was potentiated by a low concentration of forskolin (0.3 μmol/l) and the inhibitory effect of forskolin was potentiated by a low concentration of caffeine (0.1 mmol/l).”
“… forskolin to activate adenylyl cyclase, RyR1 phosphorylation in CHO-RyR1 cells expressing mAKAP increased by 42.4 ± 6.6% (… the cytosolic Ca2+ transient in CHO-RyR1 cells expressing mAKAP or mAKAP-P; however, forskolin plus 10 mm caffeine elicited a cytosolic Ca2+ transient, the … RyR1/mAKAP-P-expressing cells.”
“However, in the presence of caffeine, forskolin induced a long-term potentiation (LTP) of fEPSP.”
“Isoproterenol, forskolin , and DBcAMP enhanced this [Ca2+]i response to caffeine in control myocytes more markedly than in diabetic myocytes.”
“ Forskolin (10(-7), 3 x 10(-7) and 10(-6) M) significantly attenuated both the caffeine (1 mM)-induced EDC and caffeine (10 mM)-induced EIC.”
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