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Last Updated: 2 years ago

Possible Interaction: Caffeine and Clonidine

supplement:

Caffeine

Research Papers that Mention the Interaction

Caffeine and yohimbine had anxiogenic properties; conversely, clonidine reduced self-rated measures of anxiety across a wide spectrum of psychiatric conditions.
Psychopathology  •  1984  |  View Paper
Clonidine produced a high rate of self-biting when combined with subthreshold doses of caffeine.
Pharmacology Biochemistry and Behavior  •  1983  |  View Paper
Automutilation induced by a single large dose of clonidine was potentiated by pretreatment with methamphetamine, caffeine and theophyline, while it was inhibited by acute administration of reserpine, alpha-methyl-p-tyrosine, phenoxybenzamine, phentolamine and chlorpromazine.
Japanese journal of pharmacology  •  1977  |  View Paper
Caffeine , but not pentobarbitone, markedly enhanced the reversal of the reserpine-induced suppression of locomotor activity elicited by ET 495 + clonidine.
Acta pharmacologica et toxicologica  •  1975  |  View Paper