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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Caffeine
drug:
Cholecystokinin
Research Papers that Mention the Interaction
“Nevertheless, caffeine caused a concentration-dependent relaxation in gallbladder strips either under resting tone conditions or precontracted with 1 muM CCK.”
Characterization of intracellular Ca(2+) stores in gallbladder smooth muscle.“In the presence of 20 mM caffeine , only high concentrations of CCK , but not bombesin or JMV‐180, suppressed the caffeine‐resistant CCK or bombesin‐induced [Ca2+]c oscillations, indicating that low affinity CCK receptors inhibit agonist‐induced [Ca2+]c oscillations.”
“Similarly, caffeine induced a significant striatal expression of cholecystokinin messenger RNA in the dorsolateral and ventrolateral quadrants but was not restricted to the subcallosal area.”
“ Caffeine inhibited Ca2+ signals evoked by ACh, cholecystokinin , and ATP and also inhibited signals generated in the absence of external Ca2+.”
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