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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Caffeine
drug:
Chloroquine
Research Papers that Mention the Interaction
“… chloroquine also promoted UvrA binding to DNA, so it may be caffeine's … of UvrA. Thus, as a consequence of its interaction with DNA, caffeine inhibits these repair systems in E. coli by two entirely different mechanisms, … repair enzyme and by interfering with specific binding of the photoreactivating enzyme.”
Mechanisms of caffeine inhibition of DNA repair in E. coli.“Higher concentrations of caffeine (0.1–5 μm) and KCl (10 mM‐130 mm) produced contracture of the muscle which was sensitive to inhibition by Chlo (50–150 μm).”
“Moreover, the spike contractions superimposed on caffeine contracture were more sensitive to the inhibitory effect of Chlo than the contracture.”
Mode of inhibitory actions of acute and chronic chloroquine administration on the electrically stimulated mouse diaphragm in vitro
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