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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Caffeine
drug:
Chlordiazepoxide
Research Papers that Mention the Interaction
“Based on Eysenck's theory it was predicted that the CNV would increase after administering chlordiazepoxide and would decrease after administering caffeine.”
The effects of a depressant and a stimulant drug on the contingent negative variation“ CDP suppressed activity, caffeine increased activity and the two drugs in combination had antagonistic effects.”
“ CDP suppressed aggression, caffeine also suppressed aggression and the two drugs together had additive effects.”
“In drug interaction test sessions caffeine (56 mg/kg) blocked the discriminative stimulus properties of the training dose of CDP and shifted the CDP discriminative dose-response function to the right.”
Perceptual masking of the chlordiazepoxide discriminative cue by both caffeine and buspirone“ CDP , but not L-PIA, produced dose-related decreases in drug-lever responses when combined with training doses of caffeine or theophylline.”
“After presession treatment with intermediate doses of caffeine , 8-phenyltheophylline or 3-isobutyl-1-methylxanthine, the increases is suppressed responding produced by CDAP often were larger than those produced by CDAP alone.”
“ Caffeine (20 and 40 mg/kg) reduced the time spent in social interaction and this effect was antagonized by chlordiazepoxide , U-43,465 and DL-propranolol, but not by flumazenil, 2-chloroadenosine or clonidine.”
“It is suggested that the reversal of caffeine's effects by chordiazepoxide may have been "functional," i.e., merely a cancellation of two opposite effects.”
Caffeine-induced anxiogenesis: The role of adenosine, benzodiazepine and noradrenergic receptors
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