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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Caffeine and Chlorambucil

supplement:

Caffeine

Research Papers that Mention the Interaction

In a combined study, in vivo and in vitro, lymphocytes taken from 2 leukemic patients who had been given chlorambucil (CBC) or Ara-C by injection 3 h before, and then treated with caffeine in vitro, were found to have synergistically increased exchange frequencies.
Mutation research  •  1983  |  View Paper
Combined treatment with CBC and caffeine (CAF) strongly increased the frequency of aberrations, but had no effect on the yield of SCEs.
Mutation research  •  1992  |  View Paper
The teratogenicity of chlorambucil was also significantly potentiated by caffeine at 50 mg/kg, but similar potentiation was not observed for x-ray, MNNG, thio-TEPA, and cyclophosphamide.
Teratology  •  1983  |  View Paper