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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Caffeine and Carmustine



Research Papers that Mention the Interaction

Caffeine potentiation of BCNU-induced SCEs was also time dependent and was eliminated by a delay of 6 h between BCNU treatment and addition of caffeine.
Our results suggest that caffeine potentiates BCNU cytotoxicity and induction of SCEs by a mechanism that is independent of repair of alkylation products, but that may depend on alterations of cellular replication in BCNU-treated cells.
The synergistic effect of caffeine on cellular toxicity diminished when caffeine was added 6 to 24 h after treatment of BCNU.
Cancer research  •  1987  |  View Paper