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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Caffeine
drug:
Carboplatin
Research Papers that Mention the Interaction
“ Caffeine increased CPt cytotoxicity in K562 cells and its doxorubicin-resistant subline (K562/ADM), but little effect was seen in HL-60 cells or mononuclear cells from leukemic patients.”
“ Caffeine synergistically potentiated cytotoxicity and apoptosis induced by ionizing radiation or carboplatin (CPt), but attenuated induction of apoptosis by daunorubicin (DNR) in KG-1a cells.”
“ Caffeine synergistically reduced the level of the apoptosis inhibitor glutatione after irradiation or CPt treatment.”
Expression of apoptosis-related oncoproteins and modulation of apoptosis by caffeine in human leukemic cells
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