Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Caffeine and Anticholinergic Agents

Research Papers that Mention the Interaction

Pharmacological studies have shown that caffeine and methyl-phenidate can increase mental acuity, in direct opposition to anticholinergic drugs such as diphenhydramine.
Hong Kong medical journal = Xianggang yi xue za zhi  •  2006  |  View Paper
The anticataleptic effect of anticholinergics was potentiated when a low dose of caffeine (1 mg/kg) was applied simultaneously.
These results indicate that low doses of caffeine enhance the anticataleptic actions of muscarinic antagonists, and leave open the possibility of using caffeine as adjunctive therapy to reduce the doses and the adverse effects of anticholinergics in Parkinson's disease.
Neuropharmacology  •  2003  |  View Paper