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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Caffeine and 1-(P-Hydroxybenzyl)-6,7-Dihydroxy-1,2,3,4-Tetrahydroisoquinoline

supplement:

Caffeine

supplement:

1-(P-Hydroxybenzyl)-6,7-Dihydroxy-1,2,3,4-Tetrahydroisoquinoline

Research Papers that Mention the Interaction

“Ephedrine produced a significant BPM dose response from 0.5 to 5.0 µM. Caffeine increased BPM only at a toxic level of 250 µM. Adding caffeine to PEA or higenamine but not ephedrine further increased BPM.”
A beating heart cell model to predict cardiotoxicity: effects of the dietary supplement ingredients higenamine, phenylethylamine, ephedrine and caffeine.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2015  |  View Paper