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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Butyric Acid
drug:
Tributyrin
Research Papers that Mention the Interaction
“On a molar basis TB was 3- to 4-fold more potent than BA , whereas MB was much less potent than BA.”
“On a molar basis TB was about 4-fold more potent than either BA or MB for inducing differentiation of HL60 cells.”
Tributyrin: a prodrug of butyric acid for potential clinical application in differentiation therapy.“ TB administration resulted in increased colonic tissue concentrations of BA (p<0.05) compared with the control animals.”
The chemopreventive activity of the histone deacetylase inhibitor tributyrin in colon carcinogenesis involves the induction of apoptosis and reduction of DNA damage.“Compared to controls, rats treated with TB presented increased (p < 0.05) hepatic levels of BA indicating its effectiveness as a prodrug.”
“Analysis of short chain fatty acids in the feces after 6 months in tributyrin feeding showed a 10-fold increase in butyric acid.”
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