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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Butylated Hydroxytoluene
supplement:
Vitamin K
Research Papers that Mention the Interaction
“The results further indicate that rats receiving a high dose of BHT have a higher vitamin K requirement than would otherwise be considered necessary.”
The dose-dependent effect of BHT (butylated hydroxytoluene) on vitamin K-dependent blood coagulation in rats.“The antioxidants butylated hydroxytoluene , nor-dihydroguaiaretic acid) caused apparent non-competitive inhibition of vitamin K3 redox cycling.”
“Conversely, the concentration of vitamin K in the feces from rats receiving BHT increased more than that from control rats.”
“The concentration of vitamin K in the liver of rats receiving BHT was reduced as compared to that of control rats.”
“Hemorrhagic death, hemorrhage and a decrease in prothrombin index caused by 1.20% BHT were prevented by simultaneously adding phylloquinone (0.68 mumole/kg/day).”
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