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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Butylated Hydroxytoluene and Piperonyl Butoxide

Research Papers that Mention the Interaction

Studies with the cytochrome P450 inhibitor, piperonyl butoxide , indicated that metabolism of BHT was required for both its acute and chronic effects.
Toxicology  •  1994  |  View Paper
Administration of SKF 525-A or piperonyl butoxide to mice treated with BHT prevented the increase in thymidine incorporation into pulmonary DNA.
SKF 525-A and piperonyl butoxide completely prevented the BHT-induced increase in pulmonary DNA synthesis even when given 1–2 hr after BHT and a partial protective effect was evident when they were given 6–12 hr after BHT.
Toxicology and applied pharmacology  •  1980  |  View Paper