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Discover Supplement-Drug Interactions

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Possible Interaction: Butylated Hydroxytoluene and Factor Ix

Research Papers that Mention the Interaction

Levels of factors II, VII, X and IX were reduced 36-60 hr after BHT treatment, but by 72 hr, those most affected (VII and IX) showed some recovery and X had returned to normal.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  1987  |  View Paper
The plasma concentrations of factors II, VII, IX and X were significantly reduced in a time-dependent fashion when BHT was administered for 2–7 days and haemorrhages in epididymis were found in rats given BHT for 4–7 days.
These results suggest that factors II, VII, IX and X rapidly decrease immediately after the administration of BHT , but hypoaggregability of washed platelets reported previously may be a secondary defect caused by bleeding.
Archives of Toxicology  •  1986  |  View Paper