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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Buthionine Sulfoximine and Iron, Dietary

Research Papers that Mention the Interaction

On the other hand, phosphopeptides derived from milk casein and known to carry iron across cell membranes, markedly potentiated the toxic action of BSO when loaded with iron but were ineffective in sodium form.
Neurotoxicology  •  2013  |  View Paper
Treatment with sub-maximal concentrations of the inhibitor of GSH synthesis buthionine sulfoximine BSO ), in conjunction with iron and MPP+, produced massive cell death, whereas treatment with BSO plus MPP+ under low iron conditions did not damage neurons.
Journal of Neural Transmission  •  2010  |  View Paper
The viability-reducing effects of BSO were attenuated by ferroptosis inhibition and enhanced by iron , indicating that BSO induced ferroptosis in cancer cells.
Oncology letters  •  2018  |  View Paper
It is found that BSO crystals doped with iron and cobalt have a highersensitivity and much wider spatial-frequency range, where the effect of the amplification can be observed,compared with nondoped crystals.
Applied optics  •  1995  |  View Paper