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Discover Supplement-Drug Interactions

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Possible Interaction: Buprenorphine and Caffeine



Research Papers that Mention the Interaction

Dopamine D1‐ and D2‐receptor bockade, depletion of stored dopamine, and inhibition of dopamine synthesis could reduce the ambulation increased by single administration of morphine, buprenorphine and caffeine, and by combined administration of morphine and buprenorphine with caffeine.
The combination of morphine, buprenorphine and pentazocine with caffeine generally enhanced the effect.
The development of cross‐sensitization to morphine (10 mg kg−1) by the repeated treatment with buprenorphine (0·3 mg kg−1) was inhibited by caffeine (10 mg kg−1).
The repeated administration of caffeine (10 mg kg−1) with buprenorphine (0·3 mg kg−1) resulted in a decrease in the effect to the level of caffeine alone.
The Journal of pharmacy and pharmacology  •  1994  |  View Paper