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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Bupivacaine
supplement:
Phosphatidylinositol 4,5-Diphosphate
Research Papers that Mention the Interaction
“The mutated GIRK1 and GIRK2 (GIRK1/2) channels containing the high-affinity phosphatidylinositol 4,5-bisphosphate (PIP2) domain from IRK1, on the other hand, showed dramatically less inhibition with bupivacaine.”
Mechanism underlying bupivacaine inhibition of G protein-gated inwardly rectifying K+ channels
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