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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Bupivacaine
supplement:
Mct/Lct Lipid Emulsion
Research Papers that Mention the Interaction
“Bupivacaine 5.10−5 m‐induced conduction blocks (8/8 preparations): LCTE 0.5% suppressed the bupivacaine 5.10−5 m‐induced conduction blocks (1/8 preparations).”
“Exposure to bupivacaine 10−6 m, 10−5 m, and 5.10−5 m alone or in the presence of LCTE 0.5% resulted in a significant decrease in action potential duration measured at 50% and 90% repolarization (APD50 and APD90; P < 0.01 vs. control group).”
“ LCTE inhibited the Purkinje fibers conduction blocks induced by bupivacaine.”
“Moreover, LCTE 0.5% attenuates the decrease in Vmax induced by bupivacaine 10−6 m and 10−5 m.”
“The decrease in Vmax resulting from bupivacaine 10−5 m alone was significantly less in the presence of LCTE 0.5% (P < 0.01 vs. bupivacaine 10−5 m alone).”
Effect of long‐chain triglyceride lipid emulsion on bupivacaine‐induced changes in electrophysiological parameters of rabbit Purkinje cells
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