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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Bupivacaine
supplement:
Linolenic Acid
Research Papers that Mention the Interaction
“Reduction of bupivacaine - induced INa block was greatest in cells treated with linolenic acid.”
Fatty acids antagonize bupivacaine - induced INa blockade“In addition, linolenic acid-mediated inhibition of vasodilation induced by a toxic concentration (3 × 10−4 M) of bupivacaine seems to be partially associated with inhibition of the nitric oxide–cGMP pathway.”
“ Linolenic acid decreased cGMP levels produced by bupivacaine and sodium nitroprusside.”
“ Linolenic acid inhibited acetylcholine- and bupivacaine-induced phosphorylation of endothelial nitric oxide synthase.”
Linolenic Acid Attenuates the Vasodilation Induced by Acetylcholine in Isolated Rat Aortae
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