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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Bupivacaine and Leucine

supplement:

Leucine

Research Papers that Mention the Interaction

Forced vital capacity … decreased with bupivacaine (3.6+/-0.5 L … 3.5+/-0.4 L , P<0.05) and ropivacaine (3.2+/-0.4 L to 3.1+/-0.5 L, P<….05), but not with levobupivacaine (3.6+/-0.5 L to 3.4+/-0.6 L).
International journal of obstetric anesthesia  •  2010  |  View Paper
The convulsant activity of bupivacaine was significantly modified by only high doses of L in a dose-dependent manner.
Life sciences  •  1995  |  View Paper
The activity of potent proteolytic enzyme, cathepsins B and L (assayed against a new synthetic substrate succinyl-Tyr-Met-naphthylamide), gradually increased and reached a plateau value that was 11-fold greater than the control 48 h after bupivacaine injection.
Journal of cell science  •  1986  |  View Paper
Forced vital capacity was significantly decreased with bupivacaine (3.0 ± 0.4 L to 2.7 ± 0.3 L , P < 0.05) and ropivacaine (2.9 ± 0.4 L to 2.5 ± 0.4 L, P < 0.05) while there were no difference between two groups.
International journal of clinical and experimental medicine  •  2014  |  View Paper