Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 6 months ago

Possible Interaction: Bupivacaine and Intralipid

supplement:

Intralipid

Research Papers that Mention the Interaction

However, both Intralipid and Lipofundin partly relieve Nav1.5 from block by bupivacaine.
Anesthesia and analgesia  •  2013  |  View Paper
To conclude, 4 mL/kg of Intralipid expedited cardiovascular recovery from bupivacaine cardiotoxicity mainly by increasing systemic vascular resistance.
Human & experimental toxicology  •  2017  |  View Paper
One of the mechanism of the beneficial effects was probably that Intralipid injection increases the apparent volume of bupivacaine distribution and that decreases blood concentration. [
Zhonghua yi xue za zhi  •  2009  |  View Paper
Recent case reports have suggested that Intralipid (Fresenius Kabi) is an effective therapy for cardiac toxicity from high systemic concentrations of, e.g. bupivacaine , even though the mechanism behind the interaction is not fully clear yet.
Electrophoresis  •  2010  |  View Paper