“ Glucosamine was able to protect the articular cartilage by reducing the inhibition of proteoglycan metabolism of 0.5% Bupivacaine from 85 to 30% (p < 0.001).”
“When added after ….5% Bupivacaine …, Glucosamine allowed some recovery with inhibition of metabolism to 70% (p = 0.004).ConclusionOur results showed that all local anaesthetic solutions inhibited proteoglycan … in articular cartilage and the addition of Glucosamine was able to reduce the inhibition of metabolism caused by 0.5% Bupivacaine.”