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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Bumetanide
supplement:
Manganese
Research Papers that Mention the Interaction
“Bumetanide produced no effect on glutamine accumulation; however, because of bumetanide treatment, manganese was increased in the brain, and also the activity of gamma-glutamyl transferase in plasma; thus, we consider that the influence of bumetanide and similar diuretics on liver function and manganese homeostasis should be further studied.”
Bumetanide increases manganese accumulation in the brain of rats with liver damage.
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