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Discover Supplement-Drug Interactions

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Possible Interaction: Bumetanide and Genistein



Research Papers that Mention the Interaction

Finally, the NKCC1 inhibitor, bumetanide fully antagonized the vasorelaxant responses to genistein against phenylephrine- or KCl-induced contractions, with IC50=2.0+/-0.2 microM and 1.6+/-0.5 microM, respectively (n=6 for condition).
European journal of pharmacology  •  2006  |  View Paper
The secretory effect of genistein was dependent on the presence of Cl- and was blocked by inhibitors of Cl- secretion like bumetanide , an inhibitor of the Na(+)-K(+)-Cl- cotransporter, or 5-nitro-2-(3- phenylpropylamino)-benzoate (NPPB), a Cl- channel blocker.
European journal of pharmacology  •  1996  |  View Paper