supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago
drug:
Bumetanide
supplement:
Capsaicin
Research Papers that Mention the Interaction
“ Bumetanide , A889425 and the Akt inhibitor Akti prevented the Rb+ uptake response to capsaicin.”
TRPV1 activation stimulates NKCC1 and increases hydrostatic pressure in mouse lens.“Furthermore, the administration of bumetanide onto the spinal cord reduced the increment in DRR activity produced by CAP.”
“ Spinal bumetanide at 10 and 100 microM blocked neurogenic edema when it was administered before CAP injection, but only bumetanide at 100 microM administered after CAP injection reduced the paw edema significantly.”
Role of the Na+-K+-2Cl- cotransporter in the development of capsaicin-induced neurogenic inflammation.“The administration of capsaicin on frog skin incubated with bumetanide caused inhibition of the reaction to mechanical stimulation, whereas during incubation with amiloride no changes were recorded in PD and dPD of the skin.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback