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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Budesonide
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“Plasma cortisol levels increased and an adrenocorticotropic hormone test showed improved adrenocortical response in both budesonide groups , indicating improved safety.”
A double-blind, placebo-controlled steroid-sparing study with budesonide Turbuhaler in Japanese oral steroid-dependent asthma patients. Japanese Pulmicort Turbuhaler study group.“Significantly larger drops in serum ACTH were found in the 10-mg prednisone group (−40.7%; p = 0.04) and 9-mg budesonide group (−36.6%; p = 0.02) compared to the 3-mg budesonide group (+19.0%).”
“However, these benefits are offset by higher treatment-related adverse event rates and more frequent adrenocorticoid suppression in patients receiving budesonide.”
“After 8 weeks of oral budesonide 9 mg per day, basal cortisol levels and response to ACTH was reduced compared to placebo in 69% and 50% of patients, respectively.”
“However, these benefits are offset by higher treatment-related adverse event rates and more frequent adrenocorticoid suppression in patients receiving budesonide.”
“In contrast, the response to a low (physiological) dose of ACTH (0?5mg 1?73m) was dampened in *30% patients on treatment with beclomethasone dipropionate (BDP) or budesonide (BUD) (daily dose *500 mg m) (4).”
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