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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Bromodeoxyuridine
supplement:
Tretinoin
Research Papers that Mention the Interaction
“Treatment of N2A cells with atRA produces a reduction in phosphohistone 3 immunostaining and BrdU incorporation, both indicators of a reduction in cell proliferation.”
The all-trans retinoic acid (atRA)-regulated gene Calmin (Clmn) regulates cell cycle exit and neurite outgrowth in murine neuroblastoma (Neuro2a) cells.“ Retinoic acid induced numerous changes within h. Bromodeoxyuridine caused larger numbers of changes, whereas Delta 205 caused a more limited number.”
“Using 10-fold lower concentrations (100-500 nM), we found that ATRA inhibits MB (DAOY, D283, D425, and D458) cell proliferation as determined by cell viability [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] and bromodeoxyuridine incorporation assays.”
“ Retinoic acid induced numerous changes within h. Bromodeoxyuridine caused larger numbers of changes, whereas Δ205 caused a more limited number.”
Retinoic acid, bromodeoxyuridine, and the Δ205 mutant polyoma virus middle T antigen regulate expression levels of a common ensemble of proteins associated with early stages of inducing HL-60 leukemic cell differentiation
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