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“A high concentration of glucose (25 mM) significantly increased the level of [3H]thymidine incorporation, the level of 5-bromo-2'-deoxyuridine incorporation, and the number of cells.”
“The … BrdU into beta cells was affected … a dose-dependent manner by glucose ; over a 10-fold increase of beta-cell BrdU labeling was observed when glucose concentration was raised from ….5 to 16.7 mM. The system proved advantageous for studying the replication potential of adult beta cells.”