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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Bromocriptine
supplement:
Yohimbine
Research Papers that Mention the Interaction
“Surprisingly, the DRD2 antagonist domperidone did not counteract the effect of bromocriptine on GSIS, whereas yohimbine , an antagonist of the alpha2-adrenergic receptors, completely abolished bromocriptine-induced inhibition of GSIS.”
The dopamine receptor D2 agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the alpha2-adrenergic receptors in beta cells.“Acute concurrent yohimbine treatment as well as chronic prior sympatholytic dopamine agonist treatment ( bromocriptine plus SKF38393) simultaneously strongly aborgated or abolished all these humoral hypersensitivity responses to intravenous NE in ob/ob mice (P<0.05).”
“In pineal gland, the suppressive effects of bromocriptine and quinpirole on NAT activity were blocked by yohimbine , a selective alpha-2 adrenergic receptor antagonist, but not by spiperone, a D2-dopamine receptor antagonist.”
“ Yohimbine (0.3 mg/kg) partially antagonised the inhibitory effect of bromocriptine on stimulation-induced pressor responses.”
“ Bromocriptine (intravenous and intraluminal) stimulated ileal and colonic water absorption, which was inhibited by haloperidol and yohimbine , and reversed cholera toxin-induced ileal secretion.”
“ Yohimbine selectively and rapidly reversed the inhibiting effects of bromocriptine on single twitches, although they could not easily be reversed by washing.”
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