Possible Interaction: Bromocriptine and Glucose

“GH levels during octreotide or bromocriptine testing were decreased more significantly in OG responders than in nonresponders (P < 0.05, P < 0.05, respectively).”

“On the other hand, a dose‐dependent acute suppressive effect of bromocriptine on plasma IRI response to oral glucose was observed, suggesting a direct effect of bromocriptine on the release of insulin from beta cells.”

“Thus bromocriptine treatment improved glucose disposal in a glucose intolerant model, enhancing both NHGU and nonHGU.”

“ Bromocriptine treatment for 14 days significantly reduced body fat by 60% and areas under the glucose and insulin curves during a glucose tolerance test by 50 and 46%, respectively.”

“ Bromocriptine reduced by 45, 20 and 13% the high levels of triglyceride, glucose , and cholesterol, respectively, that were found in control pigs near sunset.”

“Both rates increase, but since Bromocriptine effects on glucose production rate is more significant than the ones on glucose utilization, the final results is an increase in plasma glucose levels.”

“We found … subjects, bromocriptine administration in the evening resulted in a significantly higher post-… sensitivity as compared with the pre-exposure visit ( glucose area under the curve (AUC) 742 mmol/L * 120 min (695–818) vs 641 (…), P = 0.036, AUC for insulin did not change, P = 0.575).”