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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Bromocriptine
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“ BMC also attenuated the AII-induced increase in cytoplasmic calcium , partially through an inhibition of cytoplasmic inositol 1,4,5 triphosphate production.”
Down-regulation of D2 dopamine receptor and increased protein kinase Cmu phosphorylation in aldosterone-producing adenoma play roles in aldosterone overproduction.“ Bromocriptine , a dopaminergic inhibitor of endogenous PRL secretion, significantly decreased calcium ion deposit rate and calcium resorption rate in femur, tibia, vertebrae 5 and 6, and sternum by 20–42%.”
Bone calcium turnover, formation, and resorption in bromocriptine- and prolactin-treated lactating rats“It is thought this inhibitory effect of bromocriptine may be mediated by inhibiting the influx of extracellular calcium and the release from intracellular calcium stores , through the activation of dopaminergic D2-receptors located in the rat adrenomedullary chromaffin cells.”
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