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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Bromelains and Streptozocin

supplement:

Bromelains

Research Papers that Mention the Interaction

Investigating the molecular mechanism underlying these effects, STZ injection caused significant increase in hepatic oxidized-LDL (Oxi-LDL) and lysophosphatidic acid (LPA) levels and hepatic lysophosphatidic acid receptor 1 (LPAR1), and beta secretase (BACE1) protein tissue expressions, while bromelain significantly aborted these effects.
Thus, STZ caused upregulation of Oxi-LDL/LPA/LPAR1/BACE1 pathway, while bromelain significantly ameliorated these effects.
Life sciences  •  2021  |  View Paper