Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 months ago

Possible Interaction: Bromelains and Fluorouracil

supplement:

Bromelains

Research Papers that Mention the Interaction

Further, the efficacy of cisplatin and 5-FU are enhanced by adjuvant treatment with bromelain , indicating that the barrier function of MUC1 may be affected.
Further, bromelain in combination with either 5-FU or cisplatin, the efficacy of the chemotherapeutic drug is enhanced.
Other studies have also indicated that there is a greater accumulation of 5-FU in the cell compartment on treatment with 5-FU and bromelain.
Cancer investigation  •  2013  |  View Paper
Bromelain significantly reduced the number of lung metastasis induced by LLC transplantation, as observed with 5-FU.
Planta medica  •  2007  |  View Paper