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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Bromelains
drug:
Crizotinib
Research Papers that Mention the Interaction
“It was thought that the intake of bromelain could result in a decrease in the bioavailability of ALC, CER, and CRZ due to bromelain-induced alkalizing effect following digestion.”
“Thus, attention should be paid to avoid the intake of bromelain with CER or CRZ.”
Development and validation of UPLC-MS/MS method for the simultaneous quantification of anaplastic lymphoma kinase inhibitors, alectinib, ceritinib, and crizotinib in Wistar rat plasma with application to bromelain-induced pharmacokinetic interaction.
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