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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Bromelains and Aldesleukin

supplement:

Bromelains

Research Papers that Mention the Interaction

Bromelain also inhibited PMA-induced IL-2 , IFN-gamma, and IL-4 mRNA accumulation, but had no effect on TCR-induced cytokine mRNA production.
Journal of immunology  •  1999  |  View Paper
Additionally, bromelain did not affect TCR and CD28-induced proliferation of highly purified CD4+ T cells, but did inhibit IL-2 production by these cells.
However, despite increased T cell proliferation, bromelain concomitantly decreased IL-2 production in splenocyte cultures.
Cellular immunology  •  2001  |  View Paper