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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Bradykinin
supplement:
Tretinoin
Research Papers that Mention the Interaction
“In conclusion, retinoids inhibit bradykinin B1 receptor-sensitized responses and this action could participate in their anti-inflammatory and immunomodulatory effects.”
Retinoids inhibit bradykinin B1 receptor-sensitized responses in human umbilical vein.“However, when we used subtoxic doses, we demonstrated that retinoids in vitro could inhibited arachidonate mobilization and eicosanoid biosynthesis induced in fibroblast cultures by PMA, calcium ionophore A23187 or bradykinin.”
Effect of retinoids on dermal inflammation and on arachidonic acid mobilization and metabolism in murine 3T6 fibroblasts retinoids, arachidonate release and metabolism.“Externally added PGJ2, at a concentration of 10 microM, can mimic the inhibitory effect of bradykinin on the loss of density-arrest induced by RA suggesting that PGJ2 is a possible candidate for being the bradykinin induced growth-inhibiting prostaglandin.”
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