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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Bradykinin
supplement:
Procaine
Research Papers that Mention the Interaction
“In the cells stimulated with bradykinin and acetylcholine, 10 μM each of procaine and lidocaine significantly inhibited NO production by 35% and 20%, respectively.”
Local anesthetics inhibit nitric oxide production and L-arginine uptake in cultured bovine aortic endothelial cells.“ Procaine , lidocaine, ropivacaine, bupivacaine, and tetracaine suppressed the bradykinin-induced PLD activation.”
“Cardiac autonomic blockade with intrapericardial procaine abolished all responses to bradykinin and phenylbiguanide.”
“3 The non‐specific K+ channel inhibitors, tetraethylammonium and procaine , reduced vasodilator responses to bradykinin and cromakalim but not those to nitroprusside in the perfused heart treated with nitroarginine and indomethacin.”
“However, sodium salicylate and procaine were ineffective against the action of bradykinin or eledoisin administered into the mesenteric artery.”
“Sodium salicylate and procaine blocked the effect of histamine and acetyylcholine given into the mesenteric artery and also abolished that of bradykinin injected into the femoral artery.”
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