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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Bradykinin and Hydroxocobalamin

Research Papers that Mention the Interaction

NG-nitro-l-arginine methyl ester and ODQ (inhibitors of nitric oxide [NO] synthase and guanylyl cyclase, respectively) and the NO scavenger hydroxocobalamin , either alone or in combination, shifted the bradykinin concentration-response curve to the right.
Hypertension  •  2004  |  View Paper
The guanylyl cyclase inhibitor ODQ and the NO scavenger hydroxocobalamin induced a larger shift of the bradykinin CRC than the NO synthase inhibitor L‐NAME, although all three inhibitors equally suppressed bradykinin‐induced cGMP responses.
British journal of pharmacology  •  2004  |  View Paper
The NO synthase inhibitor N (G)-nitro-L-… (L-NAME; 100 microM) and the NO scavenger hydroxocobalamin (200 microM) each produced … shift in the bradykinin concentration-response curve [pEC(50): L-NAME, 8.9+/-0.1 ( n =… <0.01); hydroxocobalamin, 8.3+/-0.2, ( n =6; P <0.001)].
Clinical science  •  2002  |  View Paper
Hoe 140 and hydroxocobalamin fully blocked the inotropic effect of bradykinin.
Journal of hypertension  •  2001  |  View Paper