supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Bradykinin
supplement:
Gossypol
Research Papers that Mention the Interaction
“Over the same concentration range gossypol abolished the vasodilator action of BK (1.0 nmol), however it also blocked the endothelium‐independent vasodilator response to sodium nitroprusside (30 nmol) and the vasoconstrictor effect of endothelin‐1 (10 pmol) which suggests non‐specific toxic actions of gossypol.”
Effects of bradykinin in the rat isolated perfused heart: role of kinin receptors and endothelium‐derived relaxing factor“In myometrial strips, gossypol (1-30 microM) produced rightward displacements of the cumulative concentration-response curves to acetylcholine, bradykinin and oxytocin, accompanied by reductions in maximal responses.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback