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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Bradykinin
supplement:
Epinephrine
Research Papers that Mention the Interaction
“In turn, both of the vasoactive peptides of these systems, bradykinin and angiotensin II, stimulate epinephrine production from the adrenal medulla.”
ENDOTHELIAL CELL FUNCTIONS IN THE HEMODYNAMIC RESPONSES TO STRESS *“The possibility of bradykinin being a mediator in the coronary vasodilation produced by epinephrine has been discussed.”
“The underlying mechanism in HAE is related to bradykinin dysregulation which causes these attacks not to respond to common treatment strategies including epinephrine/corticosteroid or adrenaline.”
“With the use of fluorescent Ca(2+) dye, it was found that epinephrine and isoprenaline, a beta-adrenoceptor agonist, induced endothelial Ca(2+) influx in the presence of bradykinin.”
Epinephrine-induced Ca2+ influx in vascular endothelial cells is mediated by CNGA2 channels.“Chronically elevated levels of epinephrine , occurring after vagotomy, desensitize peripheral β2‐adrenergic receptors and lead to enhancement of bradykinin hyperalgesia.”
“ Bradykinin significantly reduced the incidence of ectopic beats and epinephrine increased the incidence of nonsustained runs of VT.”
“The SCC response to bradykinin and acetylcholine are attenuated with prior stimulation by 10 microM‐adrenaline.”
“ Bradykinin increased dose-dependently norepinephrine and epinephrine release, particularly when converting enzyme was inhibited.”
“ bradykinin increased dose dependently the noradrenaline and adrenaline release in particular when the converting enzyme was inhibited.”
“The α/β‐adrenoceptor agonist adrenaline (100 μg kg−1) caused modest inhibition of leakage induced by BK , but not of the leakage response to PAF.”
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