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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Botulinum Toxins, Type A and Epinephrine

Research Papers that Mention the Interaction

Botulinum toxin type A reconstituted in 1% lidocaine with epinephrine 1:100,000 may increase the duration and efficacy of this widely used toxin.
Cutis  •  2013  |  View Paper
At 4, 30, and 90 days after treatment, subjective and objective improvement scores revealed that EPI enhanced the efficacy of BOTOX when compared to BOTOX alone.
By 3 months, the effect of BOTOX and BOTOX plus EPI had peaked and continued to fall through 6 months.
Our data suggest that addition of EPI may accelerate the rate of onset as well as the short-term efficacy of BOTOX for treatment of periorbital rhytides.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]  •  2007  |  View Paper