supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Boron
drug:
Aldesleukin
Research Papers that Mention the Interaction
“ Boron supplementation up-regulated the immune-regulatory gene, interleukin 2 (IL2) and antioxidant gene, catalase (CAT) in the peripheral blood mononuclear cells (PBMC).”
Dietary boron supplementation enhances sperm quality and immunity through influencing the associated biochemical parameters and modulating the genes expression at testicular tissue.“Addition of 320 (48) and 640 (…/L (mg/kg BW) boron markedly reduced the … IgG concentrations; splenic IL-2 and IL-10 expression; the number of CD3+, CD4+ and PCNA+ cells; and increased the … of splenic CD8+ and caspase-3+ cells and promoted caspase-3 expression in CD3+ cells.”
“Supplementation of drinking water with 40 mg/L (6 mg/kg BW) boron also markedly increased splenic IL-2 expression and the CD4+/CD8+ cell ratio and reduced splenic CD8+ cell number.”
“… boron … interleukin 2 (IL-2), interferon γ (IFN-γ), interleukin 4 (IL-4), and thymosin α1 in the thymus of rats (p < 0.05), increased the … extracellular signal-regulated kinase (p-ERK) (p < 0.05), and promoted mRNA expression of PCNA and ERK1/2 in thymocytes (p < 0.05).”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback