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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Bombesin and Trypsin



Research Papers that Mention the Interaction

Infusion of 5 ng/kg.min bombesin during 30 min induced significant increases in plasma trypsin from 206 +/- 20 to 334 +/- 44 ng/ml (p less than 0.01).
Digestion  •  1987  |  View Paper
In normal subjects administration of bombesin induced large increases in serum trypsin (p less than 0.01), while serum total alpha-amylase and pancreatic alpha-amylase did not change and serum lipase showed only a modest rise (0.01 less than p less than 0.05).
Clinica chimica acta; international journal of clinical chemistry  •  1984  |  View Paper
However, the stimulatory effect of 1000 pmol kg−1 h−1 bombesin on total protein output and the activities of trypsin , chymotrypsin and amylase were significantly higher (P < 0.05) in suckling piglets.
Experimental physiology  •  2001  |  View Paper
As compared with control (saline) values, the volume of pancreatic juice and the output of trypsin and amylase were increased by treatment with bombesin.
International journal of tissue reactions  •  1990  |  View Paper
In conclusion, bombesin has a stimulatory effect on plasma trypsin release mediated by a cholinergic mechanism and different from pancreatic secretion.
Digestion  •  1990  |  View Paper