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Last Updated: 6 months ago

Possible Interaction: Bombesin and Phosphatidylinositol 4,5-Diphosphate

Research Papers that Mention the Interaction

Bombesin induces activation of both phosphatidylinositol 4,5-bisphosphate (PIP2)-specific phospholipase C (PLC) and phospholipase D (PLD).
Biological chemistry  •  1999  |  View Paper
Bombesin induced a significant increase in 32P-labelling of PI, PIP and PIP2.
Neuroscience Letters  •  1997  |  View Paper
Bombesin , 10 nM, stimulated basal formation of phosphatidyl monophosphate (InsP1), phosphatidyl 4,5-biphosphate (InsP2) and inositol 1,4,5-triphosphate (InsP3) by 128 +/- 5.2%, 147 +/- 10% and 155 +/- 5%, respectively.
Regulatory Peptides  •  1992  |  View Paper
Treatment of cells for 2 min, but not for 4 hr, with mitogenic concentrations of insulin-like growth factor I and bombesin caused a marked decrease in PtdInsP and PtdInsP2.
Advances in enzyme regulation  •  1990  |  View Paper
At its mitogenic concentrations (1-25 nM), bombesin stimulates polyphosphoinositide turnover, i.e. breakdown of phosphatidylinositol 4,5-bisphosphate and a concomitant increase in inositol phosphates in a time- and dose-dependent manner.
The Journal of biological chemistry  •  1987  |  View Paper