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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“In anesthetized, spontaneously breathing rats, intravenous infusion of bombesin or GRP significantly amplified the pulmonary chemoreflex responses to chemical stimulants such as capsaicin and ATP.”
“This sensitizing effect was further demonstrated in patch-clamp recording studies; the sensitivities of these neurons to both chemical capsaicin and ATP) and electrical stimuli were significantly enhanced by the presence of either bombesin or GRP.”
Sensitization of pulmonary chemosensitive neurons by bombesin-like peptides in rats.“Our results demonstrate that capsaicin treatment abolished or attenuated the suppression of glucose intake produced by BN and NMB but had no effect on the ability of GRP to reduce feeding.”
Capsaicin treatment differentially affects feeding suppression by bombesin-like peptides“Systemic treatment with capsaicin , a neurotoxin which damages unmyelinated peptide-containing sensory neurons, has been shown to attenuate bombesin (BBS)-induced suppression of food intake.”
“Laparotomy as well as intraperitoneal injection of capsaicin (33 and 330 microM) or hydrochloric acid (30 mM) caused a transient reduction of gastric motor activity stimulated by intravenous infusion of bombesin (200 pmol/min) and a brief fall of blood pressure (depressor effect).”
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