Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 5 years ago

Possible Interaction: Bleomycin and Vitamin E

supplement:

Vitamin E

Research Papers that Mention the Interaction

“ Vitamin E ((+)-alpha -tocopherol) decreased DNA damage induced by bleomycin.”
Cellular & molecular biology letters  •  2004  |  View Paper
“Intratracheal administration of bleomycin (6.5 U/kg body weight) to rats resulted in significant reduction of body weight, enzymic antioxidants (superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase) and non-enzymic antioxidants (reduced glutathione, vitamin C, vitamin E and vitamin A).”
Biological & pharmaceutical bulletin  •  2008  |  View Paper
“These results suggest that a high dose of vitamin E considerably reduces the fibrotic effect of bleomycin on lung tissue in mice.”
Journal of basic and clinical physiology and pharmacology  •  1993  |  View Paper
“The concentration of vitamin E VE ) in the lung tissue increased significantly after intratracheal BLM administration.”
Kokyu to junkan. Respiration & circulation  •  1990  |  View Paper
“We tested the hypothesis that a dietary supplement of vitamin E (VE) may lessen changes in pulmonary pressure-volume characteristics induced by intratracheal instillation of bleomycin.”
The European respiratory journal  •  1988  |  View Paper