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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Bleomycin
supplement:
S-Allylcysteine
Research Papers that Mention the Interaction
“Furthermore, higher phosphorylation of AKT and NF-κB p65 in IPF patient samples and murine samples was verified by immunohistochemistry while SAC could decrease the phosphorylation level of AKT and NF-κB p65 in mice stimulated with BLM.”
“Our results … that SAC dose-dependently reduced the infiltration of inflammatory …, pulmonary lesions and collagen deposition in BLM treated mice with downregulated mRNA expression levels of fibrotic genes including alpha smooth muscle actin (α-…), fibronectin, collagen I and collagen III as well as the protein level of α-SMA.”
S-allyl-l-cysteine attenuates bleomycin-induced pulmonary fibrosis and inflammation via AKT/NF-κB signaling pathway in mice.“While bleomycin instillation increased the number of myofibroblasts within the lung mesenchymal area, this change was significantly reduced by SAC treatment.”
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