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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Bleomycin
supplement:
Edetic Acid
Research Papers that Mention the Interaction
“The treatment with EDTA and DTT prevents and disrupts aggregation of BLM N431.”
Purification of overexpressed hexahistidine-tagged BLM N431 as oligomeric complexes.“The extent of mtDNA damage by BLM was decreased by the addition of EDTA.”
Mitochondrial DNA damage by bleomycin.“In E. coli or Micrococcus radiodurans as well as in Chinese hamster cells, the fast repair component detectable after treatment with ionizing radiation or bleomycin is inhibited by EDTA.”
“The known bleomycin inhibitors cobalt and EDTA were able to prevent bleomycin nucleasic activity and thus apoptotic cell death.”
Mitochondria-independent morphological and biochemical apoptotic alterations promoted by the anti-tumor agent bleomycin in Saccharomyces cerevisiae.“The presence of 0·025 M EDTA in the reaction mixture completely prevents single-strand breaks of DNA by BLM.”
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