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Last Updated: 3 years ago

Possible Interaction: Bleomycin and Caffeine

supplement:

Caffeine

Research Papers that Mention the Interaction

A number of agents which interact with membranes or inhibit DNA repair, such as ethanol, lidocaine, verapamil and caffeine , have been reported to sensitize cells to bleomycin in vitro.
Cancer surveys  •  1986  |  View Paper
The genetic effects of BLM can be modified quantitatively by thiol compounds, caffeine , hyperthermia and H2O2.
Mutation research  •  1978  |  View Paper
When applied in a combination with BLM, CAF considerably modified the kinetics of chromosome damage for a pulse (BLM alone) treatment.
Mutation research  •  1992  |  View Paper
While having no … per se, caffeine substantially enhanced the antitumor effects of the … PLM-CHP and PLM-PEP, and the bleomycins BLM-CHP and Blenoxane in rats carrying Walker 256 carcinosarcoma and/or mice carrying … ascites tumor, even at doses of phleomycin and bleomycin below the minimum effective level.
Cancer research  •  1985  |  View Paper